Coxsackie virus heart diseases.

Coxsackie virus infections and heart disease.

T he causative factors of most congenital anomalies remain unknown in spite of voluminous literature published on the subject during the last three decades. The relatively large number of known determinants of abnormalities, such as genetic factors, chromosomal aberrations, endocrine disturbances, drugs and chemicals, radiation, physical injury, malnutrition, and infection, although well docume...

Adult heart disease due to the Coxsackie virus group B.

Myocarditis, until lately out of favour, is again becoming an acceptable diagnosis. The myocardium can be attacked by many organisms such as bacteria, viruses, fungi, rickettsiae, spirochaetes, and parasites. Viruses are of special importance, and acute or chronic myocarditis has been occasionally described in such viral infections as measles, mumps, poliomyelitis, infectious mononucleosis, psi...

Pathogenesis of Coxsackie Virus Infection

The quantitative distribution of the Conn.-5 strain of Coxsackie virus in different tissues was determined by serial titration at intervals after inoculation of 4 to 5 day old mice. High titers were reached by the 2nd day in blood, heart, liver, muscle, intestine, and its contents, and these were maintained through the 8th day, except for the blood, in which the virus level fell earlier. In par...

Constrictive pericarditis following Coxsackie virus infection.

Myocarditis and Croup Caused by Coxsackie Virus

Myocarditis has long been recognized as a complication of rheumatic fever, diphtheria, scarlet fever and whooping cough. It also occurs in association with poliomyelitis and more rarely with other virus infections such as influenza, mumps, psittacosis, infectious mononucleosis, primary atypical pneumonia, varicella, measles, infectious hepatitis and yellow fever (Lyon, 1956; Silber, 1958). Myoc...